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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
31.82
Human Site:
Y40
Identified Species:
46.67
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
Y40
A
A
A
G
Q
R
D
Y
D
L
L
V
V
G
G
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
Y39
G
A
A
G
Q
R
D
Y
D
L
L
V
V
G
G
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
Y40
A
A
A
G
Q
R
D
Y
D
L
L
V
I
G
G
Dog
Lupus familis
XP_850181
509
55065
Y27
S
A
A
G
Q
Q
N
Y
D
L
L
V
I
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
F40
A
A
G
G
Q
Q
S
F
D
L
L
V
I
G
G
Rat
Rattus norvegicus
Q9Z0J5
526
56406
F42
A
A
G
G
Q
Q
N
F
D
L
L
V
I
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
Y30
A
L
S
G
K
K
E
Y
D
L
L
V
I
G
G
Frog
Xenopus laevis
NP_001080052
504
54666
D21
G
G
I
H
H
D
Y
D
L
L
V
I
G
G
G
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
Y116
E
G
S
E
V
Y
D
Y
D
L
I
V
I
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Y115
T
K
G
G
S
Y
D
Y
D
L
I
V
I
G
G
Honey Bee
Apis mellifera
NP_001171496
537
59227
Y54
T
A
D
Q
K
F
M
Y
D
L
I
V
I
G
G
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
Y173
E
W
L
R
D
H
T
Y
D
L
I
V
I
G
G
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
G21
A
V
I
G
G
G
S
G
G
L
A
C
A
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
F26
A
N
A
T
H
Y
D
F
D
L
F
V
I
G
A
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
Y24
M
S
T
N
T
K
H
Y
D
Y
L
V
I
G
G
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
A23
G
S
G
G
I
A
T
A
R
A
A
A
G
K
Y
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
93.3
93.3
73.3
N.A.
66.6
66.6
N.A.
N.A.
60
20
46.6
N.A.
53.3
46.6
40
20
P-Site Similarity:
100
93.3
100
100
N.A.
86.6
93.3
N.A.
N.A.
93.3
33.3
66.6
N.A.
66.6
66.6
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
44
32
0
0
7
0
7
0
7
13
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
0
7
7
38
7
82
0
0
0
0
0
0
% D
% Glu:
13
0
0
7
0
0
7
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
7
0
19
0
0
7
0
0
0
0
% F
% Gly:
19
13
25
63
7
7
0
7
7
0
0
0
13
88
82
% G
% His:
0
0
0
7
13
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
7
0
0
0
0
0
25
7
69
0
0
% I
% Lys:
0
7
0
0
13
13
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
7
7
0
0
0
0
0
7
88
50
0
0
0
0
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
38
19
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
19
0
0
7
0
0
0
0
0
0
% R
% Ser:
7
13
13
0
7
0
13
0
0
0
0
0
0
0
0
% S
% Thr:
13
0
7
7
7
0
13
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
7
0
0
0
0
0
7
82
13
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
7
63
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _